We went for creature comforts (big time) in our truck. Had we not, it is not likely we would have stayed in the business for 10 years. We loved it out on the road but, over time, that love would have faded if it was a perpetual chore to get a shower, sleep comfortably in a moving truck and find a proper bathroom. Having sleeper space adequate for our needs was also important.
One of the best things of moving into a large custom sleeper from small factory sleepers was the ability to get to our stuff without having to first moving something out of the way. It sounds like a small thing but it was important. It was great to simply open a closet, cupboard or drawer to get what we want instead of moving a box to get to the other box that contained the wanted item.