A Sprinter is not a cargo van, different classes of vehicle really, so comparisons aren't really valid. A better comparison would be a Chevy diesel van to a Chevy gas van, or a Ford diesel to a Ford Gasser, or any diesel car to a gas car. Comparing a diesel Sprinter to a gas Chevy is about like comparing a Volvo straight truck to a a 10-ft Uhaul GMC truck, since they both have boxes on the back. Yes, a Sprinter will cost more to maintain than a cargo van, just like a straight truck will cost more to maintain than a used Penske box truck. Part of the mentality in trying to compare Sprinters and cargo vans is also evident in those who think they can maintain a Sprinter just like they would a cargo van. They're different. While it's true to you can buy a three year old van for the cost of a new Sprinter engine, you can also buy a three year old Sprinter for the cost of a new big truck Cummins diesel engine.
The original question asked, advantages of diesel versus gas....
Power/Torque
Advantage: Split Decision
Typically, gas engines make more horsepower, while diesels produce more torque. Are you looking for off-the-line acceleration of an unloaded truck/van? Maybe you use yours around town where quick starts are important and you don't often tow a trailer or haul a load. If this is the case, then you'll want a gas engine. By design, gas engines rev faster and are able to reach higher rpm peaks than diesels. This allows them to attain greater horsepower numbers and quicker 0-60-mph times.
However, if towing capacity and brute pulling force are your game, a diesel is for you. The torque advantage of diesels is perfectly suited for pulling heavy loads up steep grades. Because of the relatively high-compression ratio necessary to ignite the diesel fuel (17:1 diesel versus 9:1 gas), a diesel makes all its torque and power low in the rev range. As an example, the GM 8.1L gasoline V-8 in Chevrolet and GMC pickups puts out 340 hp and 455 lb-ft of torque, while GM's 6.6L V-8 turbodiesel makes slightly less hp at only 300, but makes up for it in torque with a healthy 520 lb-ft of grunt.
Fuel Economy
Advantage: Diesel
Diesel fuel has a higher energy density than gasoline. One gallon of diesel contains approximately 147,000 BTUs of energy, while a gallon of gasoline only has 125,000 BTUs. This means it takes more gasoline to equal the power output of diesel, making diesel engines more efficient per gallon of fuel burned. Also, because diesel engines use the more efficient direct fuel-injection method (fuel injected directly into cylinder) compared to the port fuel-injection setup in gas engines where gas is mixed with incoming air in the intake manifold, the diesel system has little wasted or unburned fuel. Diesels also use about one third as much fuel at idle as gasoline units. Even though there are no official EPA-mileage figures for 3⁄4-ton and bigger trucks, you'll diesels get six to eight more mpg than similar-weight gas pickups. Over the life of the vehicle, this advantage could be significant, especially if you drive a lot of miles.
Initial Cost
Advantage: Gasoline
Because of the high-compression ratios and resulting high cylinder pressure in diesel engines, they must be built to withstand more punishment than gas engines. Beefed-up parts include a thicker block and cylinder heads and stronger connecting rods, pistons, crankshaft, and valves. These parts can be costly. As an example, if you want to upgrade an '02 F-250 from the standard 5.4L V-8 to the 7.3L turbodiesel V-8, you're going to spend around $4800. However, to go from the 5.4L to the 6.8L V-10 gasoline engine, the price is a more manageable $600. Another diesel disadvantage that comes as a byproduct of needing heavy-duty components is increased weight. A diesel engine can weigh several hundred pounds more than a comparable gas model.
Noise/Vibration
Advantage: Gasoline
Despite huge improvements in noise isolation and engine-noise technology in pickup trucks in the past 10 years, diesels are still louder and shake more than their gasoline brothers. However, a recent back-to-back drive in two Ford trucks, one equipped with a 5.4L gas V-8 and the other fitted with a 7.3L diesel V-8, demonstrated that diesels aren't that far behind. At idle, the clatter and shake of the diesel are clearly noticeable, while it's tough to tell if the gas engine is even running. Under low-speed acceleration, the diesel still makes more noise. But once you're up to speed, there's little difference between the two even when accelerating on the highway.
Cold Weather
Advantage: Gasoline
Anyone who's tried to start a diesel engine on a cold winter morning knows the winner in this category. Diesels don't have spark plugs like gasoline engines do. The fuel is ignited spontaneously once it's injected into the cylinder that's already under pressure. When it's cold (below 30), the air isn't hot enough to ignite the diesel fuel. To help counter this, today's diesel engines use a computer that senses cylinder temperature and injects the fuel later in the engine rotation. By injecting the fuel when the piston is closer to top dead center, the cylinder is under more pressure and the air inside is hotter, which aids combustion.
Short-Term Maintenance
Advantage: Gasoline
Regular maintenance on a diesel is more costly, thanks to several items including the larger volume of oil in the engine and the fact that fuel filters and water separators must be serviced more often, although Power Service or Howes reduces the service interval on these items. Modern gas engines have an advantage thanks to extended service intervals on spark plugs, though.
Long-Term Maintenance and Durability
Advantage: Diesel
The flip side of a diesel-engine's expensive initial cost is its excellent durability. Dodge, Ford, and GM learned long ago they were better off buying diesel technology from experts such as Cummins, International, Isuzu and Mercedes than spending tons of money developing it themselves. These manufacturers all have years of experience building heavy-duty, over-the-road diesels that have to log 100,000 miles a year for years on end, routinely haul heavy loads and may have to idle for days at a time. Think of the diesel engines found in GM, Ford, and Dodge pickups and SUVs as mini big-rig engines. The average gas engine is good for only around 125,000 miles before needing a rebuild and isn't designed to constantly pull a heavy load. A diesel can go more than three times this amount before needing an overhaul. It's simply in the way the piston rings work and how they are designed different for diesel engines.
Conclusion
Choosing between a gas or diesel engine comes down to what you'll do with the truck and where you live. If you use your truck like a car, desire quick, quiet acceleration, rarely haul a heavy load, and you don't plan on keeping it past 200,000 miles before pistons should be replaced, you may want to consider a gas engine. They run smoother, fuel is easier to find, and they're easier to start in cold weather. However, if you use your truck for towing or hauling freight, like good fuel economy, and plan on racking up loads of miles, diesel is an ideal choice.
If I had a choice between a Ford E-350 gasser or a diesel, I'd go with the diesel.