You did not mention the third option of adding a lift axle.
Tandem axles have several disadvantages. You will pay higher tolls. You will buy more tires over the life of the truck. Two drive axles require more maintenance and repair than one. And, they are not needed since expedited loads are light enough to be run with a single axle or lift axle, depending on truck configuration and your carrier's requirements.
With all that in mind, Diane and I spec'ed tandem drive axles when we built
our truck, a CR-unit that will seldom if ever carry more than 5,000 lbs. We did it for one reason and one reason alone: driver comfort.
When we drove fleet owner trucks, two of them were Freightliner Century Class D-units with "twin screws." We drove other trucks that were nearly identical but for the single drive axle with lift axle set up. The difference in ride was PROFOUND. Having experienced the difference first-hand, there was no way we were going to build a truck with a single drive axle, and we went with twin screws instead.
If we had it to do over again, we would do the same thing.