Power Acoustik REP4-1400, really is 640w RMS, says 140w max draw (?)
Depends on how you hook it up. 2 Ohms or 4 Ohms. Bridged at 4 Ohms it's 320 Watts x 2, so 640 Watts RMS.
The 1400 Watts thing is the PMPO - "peak music power output" and is more or less meaningless. An amp can't maintain this for much more than a split second and then only under lab conditions. From that point on, the marketing folks take over and splash this useless number all over the place. RMS is the only number worth looking at.
It's a Class A/B Full Range & Class D Monoblock Amp, so efficiency is good, with .55 or .60 for the A/B and .8 for the subs.
The fuse formula is just a general ballpark thing, mainly to let you know if they're lying or not. In your case, if you go with the 2 Ohm bridge at 640 Watts, then it's easy.
Watts / Volts = Amps
It's going to be more than 12 volts. Some vehicles (most cars, really) operate on 14.4 volts, but of course it varies with temperature and other factors, so it could be anywhere from 14.4v down to 13.2. The Sprinter will generally be between 13.2 (when it's really hot) and 14.2 (when it's Canada cold). 13.8 is a good middle of the road average for a Sprinter under most conditions.
Thus, 640W / 13.8V = 46.38A
Add in the 160 Watt Pioneer (11.59A) and you're at 58 amps.
However, possibly the most important thing that a lot of people don't think of is, that is the maximum possible sustained current the amp will draw at full (un-clipped) power. The only signal type that would require that level of power would be full volume sine waves. If you listen to MUSIC at full volume you can cut that calculated current in about half. If you turn it down at all you can probably cut it in half again.
So the in-service current draw of an amp and head unit like that is probably between 15A and 25A or less on average.
I have a monster Pioneer head unit that's 50 Watts x 4, but that's peak, not RMS. They practically hide the RMS power in the fine print. The RMS is actually 14 Watts per channel.
But I'm only powering the 4" dash speakers (which I've replaced twice).