When I ran with Panther (Cargo Van), I never turned down anything they offered me for the first 3 months. After I turned down the first load, it "seemed" that I was "bypassed" on loads I had taken in the past. I noticed, once that happened, I developed a bad attitude, and starting turning down more loads, or, started cherry picking. That's when I felt things where getting slow, and I started looking elsewhere for work.
It may be slow in general right now, but if your not taking loads offered, it's going to enhance the appearence of the slow period.
Sometimes I wonder if I would still be with Panther if I hadn't turned down that first load.