For cargo vans, Panther requires a CDL, but they do not require HAZMAT. But, in order to get a CDL for a cargo van, there must be an endorsement of some kind on the license, otherwise it's not a CDL, it's a regular Class D operator's license. So, you can get either HAZMAT, or a Passenger endorsement for a van Class C.
A passenger endorsement is certainlty cheaper than the HAZMAT background check, that's for sure. And since Panther will not put placardable HAZMAT on a van, the HAZMAT endorsement is basically a waste of money. When you are HAZMAT placarded in a van you are, in fact, a Commercial Motor Vehicle, with all the restrictions of logs and scales. Rather than mess with trying to teach a bazillion, dumb as a brick, van drivers (you know, what with turnover being what it is) how to scale and log properly so as to not get fined or put OOS for logging violations, Panther just puts all placardable HAZMAT on a straight truck, since they log every day, anyway.
You do not need a HAZMAT endorsement on your CDL to carry non-placardable HAZMAT freight. You only need the HAZMAT endorsement for a van when the HAZMAT freight requires placarding, which is generally in amounts of 1001 pounds or more. If the freight doesn't require placarding in amounts of 1000 pounds or less, no HAZMAT endorsement is needed.
If the HAZMAT requires placarding in any amount at all, even one pound (like explosives, inhilation hazards, etc) then no amount of that type of HAZMAT can be put on a van, anyway, as that type of freight must be physically separated from the drivers, as in a detached box or a trailer.
So, a Passenger Endorsement on a Class C will satisfy the CDL requirements of Panther.
The advantages of having a Class C with the HAZMAT endorsement, versus a passenger endorsement, are many, however. When you study and pass the HAZMAT test, you will have learned about HAZMAT to the point where you will know what to do and what not to do when there is a HAZMAT situation that you might come upon or be involved with, it makes you more aware of what's around you since you'll know what's inside that placarded truck next to you on the highway. If you study for and pass the Passenger Endorsement, you will have learned nothing whatsoever that will help you in your job. There are a few shippers of HAZMAT freight that require a HAZMAT endorsement on the driver's CDL, even for non-HAZMAT shipments. Then there's also the advantage of not having to deal with questions from police, border guards or other authorities about why you have a passenger endorsement on your CDL when you're hauling freight.