Not being able to fix the time zone to eastern would be a big issue with me. It's bad enough having to keep track of the ever-changing time on the cell phone. Nothing like being near a time zone border, setting the alarm on the phone, and then wake up to find the phone is now working off a different cell tower in another time zone.
As for the goofy routing, it may depend on the type of truck you set up in the profile, "over the road" or "delivery". If it's set for "over the road" I would imagine that it will highly favor Interstates, for example. And if the truck is big enough, it'll favor STAA routes, even if it's not the most direct route.
Here's a pretty intense review of the unit, lots of pics, goes through pretty much everything on how to use it.
Garmin nuvi 465T Truck GPS Review (GPSmagazine.com)
As for the goofy routing, it may depend on the type of truck you set up in the profile, "over the road" or "delivery". If it's set for "over the road" I would imagine that it will highly favor Interstates, for example. And if the truck is big enough, it'll favor STAA routes, even if it's not the most direct route.
Here's a pretty intense review of the unit, lots of pics, goes through pretty much everything on how to use it.
Garmin nuvi 465T Truck GPS Review (GPSmagazine.com)