Here's the only difinitive thing I can find from FMCSA:
391.11
General qualifications of drivers.
(a) A person shall not drive a commercial motor vehicle unless he/she is qualified to drive a commercial motor vehicle. Except as provided in
§391.63, a motor carrier shall not require or permit a person to drive a commercial motor vehicle unless that person is qualified to drive a commercial motor vehicle.
(b) Except as provided in
subpart G of this part, a person is qualified to drive a motor vehicle if he/she—
(1) Is at least 21 years old;
(2) Can read and speak the English language sufficiently to converse with the general public, to understand highway traffic signs and signals in the English language, to respond to official inquiries, and to make entries on reports and records;
(3) Can, by reason of experience, training, or both, safely operate the type of commercial motor vehicle he/she drives;
(4) Is physically qualified to drive a commercial motor vehicle in accordance with
subpart E—Physical Qualifications and Examinations of this part;
(5) Has a currently valid commercial motor vehicle operator's license issued only by one State or jurisdiction;
(6) Has prepared and furnished the motor carrier that employs him/her with the list of violations or the certificate as required by
§391.27;
(7) Is not disqualified to drive a commercial motor vehicle under the rules in
§391.15; and
(8) Has successfully completed a driver's road test and has been issued a certificate of driver's road test in accordance with
§391.31, or has presented an operator's license or a certificate of road test which the motor carrier that employs him/her has accepted as equivalent to a road test in accordance with
§391.33.
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As far as driving a CMV goes, the minimum age is definitely 21. However, would this poster be disqualified from driving a vehicle 10000 GVWR or less in interstate commerce? Can anyone point to a reg? We've never had one before, so I am still researching to find out.