Diane and I set our generator to come on automatically when battery voltage reaches 11.0 volts. This is a compromise between us. I would prefer to go lower to minimize generator hours. She would prefer higher to leave a perceived margin of safety and make it less likely that the truck will not start one day. (We're the same way with fuel. At 1/4 tank, she wants to fill up. I'm content to drive more.)
We have a big sleeper with a large refrigerator and at least one computer on almost all the time, and often two computers on. We sleep with the parking and chicken lights turned on most nights. An electric water pump gets used whenever we want to get a drink or wash up. The Qualcomm unit is on most of the time, as is the data logger for the reefer. If the generator us not being used for heat or air conditioning, the Fan-Tastic Vent (ceiling fan) is usually on. Such is the "hotel" drain in our truck.
There are five batteries on this truck. One is for the reefer. It is isolated from the rest of the truck. It serves and is charged by the reefer only. The other four batteries are the truck batteries. The sleeper, inverter and generator are tied into them. There is no hotel battery or battery bank.
When the truck runs, the truck alternator charges the batteries. When the truck is plugged into shore power, shore power charges the batteries. When the generator is running (like all day and night so we can run the air conditioning), the generator charges the batteries. If nothing is running and the battery voltage drops below 11 volts, the generator automatically kicks in to charge the batteries and automatically turns off when the batteries are charged.
The 11 volt setting seems not to have hurt us any. We purchased four Optima, yellow top, 900 cold cranking amp, batteries in July, 2009. Three years later they are still going strong.
There was an immediate and noticeable difference when they were installed. With the old batteries, the generator used to kick in around 5:00 a.m. to charge the batteries on a typical layover night. With the Optima batteries the generator does not kick in at all on a typical layover night.
Our truck is wired such that the generator must be run to run the microwave. That is because our microwave is a convection microwave that requires a lot of power if convection cooking is being done. Long before the generator would kick in to charge the batteries, we will start the generator to cook breakfast or start the truck to drive somewhere.
It has happened that we forgot to set the generator to "auto-on" and left the truck unattended. From that, we know that if the voltage drops below 10.1 volts, there is not enough power to start the generator (or the truck). The fix is to use jumper cables and the reefer battery to start the generator and then use the generator to charge up the truck batteries. It takes less than thirty minutes for the generator to charge the Optima batteries up to the level where we can start the truck.