I run a 2003 international 24 foot S/T 340,000 original miles local and regional work DT466E, allison trans, 411 rears, 11r22.5 steel hub piolot wheels.
I am a skeptic when it comes to the mechanic in a bottle mentality But here is what works for me as recomended by an old timer veteran driver.
I use Howes lubricator/Antijell year round. Yep, I swear by it, 12 oz per 50 gal fuel. Use it 10 M.P.G. at average speed 63 MPH Im back to the same milage as the pre ULSD garbage. Dont use loose at least 1 - 1.5 M.P.G.
You have water in the tank year round due to thermo conversion hot fuel returning to the tank passing through the air in the tank and then mixing with cold fuel. add water in fresh fuel as a by product from refining and dont forget winter is here this adds to it. Most additives dont stay mixed with water as well as howes B.T.W., This raises hell with the injectors as well as the whole fuel systeme. Reason? Water has no lubricity and will not burn. Also, an over treat of howes lubricator/Antijell wont hurt the engine like allot of other additives In fact you want to double dose the first fill or two with howes to make sure its at a good level. An overtreat with power service will cause performance issues untill you cut it with diesel did that one day when I was a newbee. More must be better? No, lots of smoke and no power and it didnt take much to do it.
Annother tip.
2 cans of Diesel Purge at each fuel filter change Follow the dirrections and you will be good you may need to build a rig to acess the fuel inlet so you can do the service. Been doing this for over five years and have had good luck with it.
Bob Wolf.