A driver talking about a CPM of 53c a mile is just talking of what it costs to move the truck before driver pay, profit and replacement cost. You need to know fixed costs and variable. For instance variable such as c-link, insurance, truckpayment, the more miles you run every month the less cost per mile.
The fixed cost such as fuel and wear and tear stay the same. For instance out here in Calif with fuel at $3.00 a gal. and my truck getting 10mpg I know my cost is 30c a mile for fuel and wear and tear I usually figure at 10c a mile. So I can say my cost per mile just to move the truck is 40c a mile.
Now say a team has a $1600 a month payment and drives 16,000 miles a month thats 10c a mile. A solo driving 8000 miles a month would have a CPM 20c per mile.
As far as the 53c scenario, lets say you have a $1600 truck payment per month, 16,000 miles equals 10c a mile
$400 insurance equals 2.5c a mile, fuel 30c a mile, wear and tear 10c. That is the 53c, now you have to figure what you're time effort and replacement cost is worth.